Article
The Genetics of IgA Nephropathy: An Overview from Western Countries
1 Jan 2015
Abstract excerpt
BACKGROUND: IgA nephropathy (IgAN) is the commonest primary glomerulonephritis worldwide and a significant cause of chronic kidney disease and end-stage renal disease. It is widely accepted that genetic factors play a role in the pathogenesis of IgAN. However, the identity of these genetic factors remains uncertain. SUMMARY: Critical to all genetic studies is a precise phenotypic definition of the disease. It is...
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