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Article

Genetics of IgA nephrology: risks, mechanisms, and therapeutic targets.

Pediatric nephrology (Berlin, Germany) - 1 Nov 2024

Qu Shu, Zhou Xu-Jie, Zhang Hong

Abstract excerpt

IgA nephropathy (IgAN) is a genetically complex multifactorial trait. Over the past decade, population-based genome-wide association studies (GWAS) have identified more than 30 IgAN risk loci, providing novel perspectives on both the epidemiology of the disease and its underlying molecular mechanisms. In addition, the association between IgAN and galactose-deficient IgA1 (Gd-IgA1) presented another avenue for...

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Identifiers

PMID: 38600219
DOI: 10.1007/s00467-024-06369-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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