Article
Lack of oncogenic GNAQ mutations in melanocytic lesions of the conjunctiva as compared to uveal melanoma.
Investigative ophthalmology & visual science - 1 Dec 2010
Dratviman-Storobinsky Olga, Cohen Yoram, Frenkel Shahar, Pe'er Jacob, Goldenberg-Cohen Nitza
Abstract excerpt
PURPOSE: Somatic mutations in codon 209 of the GNAQ gene are the first initiating events to be identified in uveal melanoma. The purpose of this study was to search for GNAQ209 mutations in conjunctival melanocytic lesions. METHODS: Forty archival samples of conjunctival melanocytic lesions (conjunctival nevi, primary acquired melanosis, and conjunctival melanoma), 27 samples of uveal melanoma, and 11 samples of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
