Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Retargeting of Adenovirus Vectors through Genetic Fusion of a Single-Chain or Single-Domain Antibody to Capsid Protein IX

15 Jul 2010

Abstract excerpt

Adenovirus (Ad) vectors are the most commonly used system for gene therapy applications, due in part to their ability to infect a wide array of cell types and tissues. However, many therapies would benefit from the ability to target the Ad vector only to specific cells, such as tumor cells for cancer gene therapy. In this study, we investigated the utility of capsid protein IX (pIX) as a platform for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Viral Infections and Immunology Research
Share to Viral Infectious Diseases and Gene Expression in Insects
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20631131
DOI: 10.1128/jvi.02665-09

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Retargeting of Adenovirus Vectors through Genetic Fusion of a Single-Chain or Single-Domain Antibody to Capsid Protein IXPMID 20631131Read ↗

A Strategy for Adenovirus Vector Targeting with a Secreted Single Chain AntibodySemantic proximity Read ↗

Retargeting adenoviruses for therapeutic applications and vaccinesSemantic proximity Read ↗

Targeted Adenovirus VectorsSemantic proximity Read ↗

Efficient incorporation of a functional hyper-stable single-chain antibody fragment protein-IX fusion in the adenovirus capsidSemantic proximity Read ↗

Genetic and Chemical Capsid Modifications of Adenovirus Vectors to Modulate Vector–Host InteractionsSemantic proximity Read ↗

Capsid and Genome Modification Strategies to Reduce the Immunogenicity of Adenoviral VectorsSemantic proximity Read ↗

Spacers increase the accessibility of peptide ligands linked to the carboxyl terminus of adenovirus minor capsid protein IX.Semantic proximity Read ↗

Designing adenoviral vectors for tumor-specific targeting.Semantic proximity Read ↗

A novel method for generating and screening peptides and libraries displayed on adenovirus fiberSemantic proximity Read ↗

iMATCH: an integrated modular assembly system for therapeutic combination high-capacity adenovirus gene therapySemantic proximity Read ↗

Peptide targeting of adenoviral vectors to augment tumor gene transfer.Semantic proximity Read ↗

Adenovirus – a blueprint for gene deliverySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.