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Article

Peptide targeting of adenoviral vectors to augment tumor gene transfer.

Cancer gene therapy - 1 Jul 2012

Ballard E N, Trinh V T, Hogg R T, Gerard R D

Abstract excerpt

Adenovirus serotype 5 remains one of the most promising vectors for delivering genetic material to cancer cells for imaging or therapy, but optimization of these agents to selectively promote tumor cell infection is needed to further their clinical development. Peptide sequences that bind to specific cell surface receptors have been inserted into adenoviral capsid proteins to improve tumor targeting, often in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22595794
DOI: 10.1038/cgt.2012.23
PMCID: PMC3380173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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