Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

iMATCH: an integrated modular assembly system for therapeutic combination high-capacity adenovirus gene therapy

19 Jan 2021

Abstract excerpt

Adenovirus-mediated combination gene therapies have shown promising results in vaccination or treating malignant and genetic diseases. Nevertheless, an efficient system for the rapid assembly and incorporation of therapeutic genes into high-capacity adenoviral vectors (HCAdVs) is still missing. In this study, we developed the iMATCH (integrated modular assembly for therapeutic combination HCAdVs) platform, which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Viral Infectious Diseases and Gene Expression in Insects
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33665227
DOI: 10.1016/j.omtm.2021.01.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

iMATCH: an integrated modular assembly system for therapeutic combination high-capacity adenovirus gene therapyPMID 33665227Read ↗

Advancements in the design and scalable production of viral gene transfer vectorsSemantic proximity Read ↗

Capsid and Genome Modification Strategies to Reduce the Immunogenicity of Adenoviral VectorsSemantic proximity Read ↗

The Adenovirus Vector Platform: Novel Insights into Rational Vector Design and Lessons Learned from the COVID-19 VaccineSemantic proximity Read ↗

Advances of Recombinant Adenoviral Vectors in Preclinical and Clinical ApplicationsSemantic proximity Read ↗

Dendritic cell targeting in lymph nodes with engineered modular adapters improves HAdV5 and HC-HAdV5 tumor vaccination by co-secretion of IL-2v and IL-21Semantic proximity Read ↗

Elicitation of potent SARS-CoV-2 neutralizing antibody responses through immunization with a versatile adenovirus-inspired multimerization platformSemantic proximity Read ↗

Cancer Associated Endogenous Retroviruses: Ideal Immune Targets for Adenovirus-Based ImmunotherapySemantic proximity Read ↗

A Strategy for Adenovirus Vector Targeting with a Secreted Single Chain AntibodySemantic proximity Read ↗

AdenoBuilder: A platform for the modular assembly of recombinant adenovirusesSemantic proximity Read ↗

Oncolytic adenovirus: A tool for cancer therapy in combination with other therapeutic approachesSemantic proximity Read ↗

Evolving Horizons: Adenovirus Vectors’ Timeless Influence on Cancer, Gene Therapy and VaccinesSemantic proximity Read ↗

Genetic and Chemical Capsid Modifications of Adenovirus Vectors to Modulate Vector–Host InteractionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.