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Targeted Adenovirus Vectors

1 Nov 2004

Abstract excerpt

Recombinant adenovirus (Ad) vectors continue to be the preferred vectors for gene therapy and the study of gene function because they are relatively easy to construct, can be produced at high titer, and have high transduction efficiency. However, in some applications gene transfer with Ad vectors is less efficient because the target cells lack expression of the primary receptor, coxsackievirus and adenovirus...

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Identifiers

PMID: 15610604
DOI: 10.1089/hum.2004.15.1034

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