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Genetic and Chemical Capsid Modifications of Adenovirus Vectors to Modulate Vector–Host Interactions

2 Jul 2021

Abstract excerpt

Adenovirus-based vectors are playing an important role as efficacious genetic vaccines to fight the current COVID-19 pandemic. Furthermore, they have an enormous potential as oncolytic vectors for virotherapy and as vectors for classic gene therapy. However, numerous vector-host interactions on a cellular and noncellular level, including specific components of the immune system, must be modulated in order to...

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Share to Viral gastroenteritis research and epidemiology
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34372506
DOI: 10.3390/v13071300

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