Article
Scapula development is governed by genetic interactions of Pbx1 with its family members and with Emx2 via their cooperative control of Alx1.
Development (Cambridge, England) - 1 Aug 2010
Capellini Terence D, Vaccari Giulia, Ferretti Elisabetta, Fantini Sebastian, He Mu, Pellegrini Massimo, Quintana Laura, Di Giacomo Giuseppina, Sharpe James, Selleri Licia, Zappavigna Vincenzo
Abstract excerpt
The genetic pathways underlying shoulder blade development are largely unknown, as gene networks controlling limb morphogenesis have limited influence on scapula formation. Analysis of mouse mutants for Pbx and Emx2 genes has suggested their potential roles in girdle development. In this study, by generating compound mutant mice, we examined the genetic control of scapula development by Pbx genes and their...
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