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Article

CYP2B6 polymorphism and nonnucleoside reverse transcriptase inhibitor plasma concentrations in Chinese HIV-infected patients.

Therapeutic drug monitoring - 1 Oct 2010

Chen Jun, Sun Jianjun, Ma Qing, Yao Yaming, Wang Zhenyan, Zhang Lijun, Li Li, Sun Fuyan, Lu Hongzhou

Abstract excerpt

The purpose of this study was to investigate the frequency of CYP2B6 polymorphisms and their influence on plasma concentrations of efavirenz and nevirapine in HIV-infected Chinese patients. After written informed consent, 159 patients were enrolled at Shanghai Public Health Clinical Center. Genotyping for 516 G>T, 785 A>G, 983 T>C, and 1459 T>C polymorphisms in CYP2B6, together with CYP3A4 -392 A>G, CYP3A5 6986...

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Identifiers

PMID: 20625352
DOI: 10.1097/FTD.0b013e3181ea953c

Genes

ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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