Article
CYP2B6 516 G>T polymorphism and side effects of the central nervous system in HIV-positive individuals under Efavirenz treatment: Study of a sample from southern Brazil.
Anais da Academia Brasileira de Ciencias - 1 May 2017
Müller Talise E, Ellwanger Joel H, Michita Rafael T, Matte Maria Cristina C, Renner Jane D P
Abstract excerpt
This study aimed to identify the 516 G>T polymorphism of the CYP2B6 gene and evaluate its influence on central nervous system (CNS) side effect development in HIV-positive individuals undergoing Efavirenz (EFV) treatment in a population from southern Brazil. Additionally, we performed a survey on the clinical and epidemiological characteristics of our sample. In addition to medical records evaluation, whole blood...
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