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Article

Correlation of CYP2B6-516G > T Polymorphism with Plasma Efavirenz Concentration and Depression in HIV-Infected Adults in Northern Thailand.

Current HIV research - 1 Dec 2012

Aurpibul Linda, Chotirosniramit Nuntisa, Sugandhavesa Patcharaphan, Kosashunhanan Natthapol, Thetket Sunida, Supindham Taweewat, Piyamongkol Weerawit, Supparatpinyo Khuanchai

Abstract excerpt

BACKGROUND: Single nucleotide polymorphism of the hepatic cytochrome P450 isoenzyme 2B6 (CYP2B6) gene is a cause of variation in plasma efavirenz (EFV) concentrations. We aimed to determine the allelic distribution of CYP2B6 gene, plasma levels of EFV, the prevalence of clinical depression, and their correlations in northern Thai population. METHODS: This was a cross-sectional study of HIV-infected patients on...

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PMID: 22950382
DOI: 10.2174/157016212803901338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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