Article
Gastrointestinal tract disorder in natriuretic peptide receptor B gene mutant mice.
The American journal of pathology - 1 Aug 2010
Sogawa Chizuru, Abe Asaki, Tsuji Takehito, Koizumi Mitsuru, Saga Tsuneo, Kunieda Tetsuo
Abstract excerpt
Natriuretic peptide receptor B (NPR-B), which has high affinity for C-type natriuretic peptide (CNP) and synthesizes intracellular cGMP, may be involved in gastrointestinal tract (GIT) regulation. A mutant allele of the NPR-B-encoding gene (Npr2) is responsible for the phenotype of the short-limb...
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