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Article

Smoothelin-a is essential for functional intestinal smooth muscle contractility in mice.

Gastroenterology - 1 Nov 2005

Niessen Petra, Rensen Sander, van Deursen Jan, De Man Joris, De Laet Ann, Vanderwinden Jean-Marie, Wedel Thilo, Baker Darren, Doevendans Pieter, Hofker Marten, Gijbels Marion, van Eys Guillaume

Abstract excerpt

BACKGROUND & AIMS: In patients with chronic intestinal pseudo-obstruction, intestinal motility is disturbed by either nervous or myogenic aberrations. The cause of the myogenic form is unknown, but it is likely to originate in the contractile apparatus of the smooth muscle cells. Smoothelins are actin-binding proteins that are expressed abundantly in visceral (smoothelin-A) and vascular (smoothelin-B) smooth...

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Identifiers

PMID: 16285958
DOI: 10.1053/j.gastro.2005.08.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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