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Article

A recessive screen for genes regulating hematopoietic stem cells.

Blood - 23 Dec 2010

Papathanasiou Peter, Tunningley Robert, Pattabiraman Diwakar R, Ye Ping, Gonda Thomas J, Whittle Belinda, Hamilton Adam E, Cridland Simon O, Lourie Rohan, Perkins Andrew C

Abstract excerpt

Identification of genes that regulate the development, self-renewal, and differentiation of stem cells is of vital importance for understanding normal organogenesis and cancer; such knowledge also underpins regenerative medicine. Here we demonstrate that chemical mutagenesis of mice combined with advances in hematopoietic stem cell reagents and genome resources can efficiently recover recessive mutations and...

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Source

Identifiers

PMID: 20610815
DOI: 10.1182/blood-2010-04-269951

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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