Article
GATA2 +9.5 enhancer: from principles of hematopoiesis to genetic diagnosis in precision medicine.
Current opinion in hematology - 1 May 2020
Soukup Alexandra A, Bresnick Emery H
Abstract excerpt
PURPOSE OF REVIEW: By establishing mechanisms that deliver oxygen to sustain cells and tissues, fight life-threatening pathogens and harness the immune system to eradicate cancer cells, hematopoietic stem and progenitor cells (HSPCs) are vital in health and disease. The cell biological framework for HSPC generation has been rigorously developed, yet recent single-cell transcriptomic analyses have unveiled...
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