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Article

The -351A/G polymorphism of ESR1 is associated with risk of myocardial infarction but not with extreme longevity.

Clinica chimica acta; international journal of clinical chemistry - 14 Dec 2010

Roszkowska-Gancarz Malgorzata, Kurylowicz Alina, Polosak Jacek, Ambroziak Michal, Puzianowska-Kuznicka Monika

Abstract excerpt

BACKGROUND: Women live longer than men. Some possible reasons for this advantage are the protection provided by high concentrations of 17β-estradiol (E2) during the premenopausal period and polymorphic variants of the estrogen receptors (ERs), which mediate various cardiovascular functions of E2. METHODS: We tested whether the -351A/G and -397T/C polymorphisms of the ERα-encoding ESR1 were associated with extreme...

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Source

Identifiers

PMID: 20599431
DOI: 10.1016/j.cca.2010.06.028

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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