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Article

Association between ESR2 genetic variants and risk of myocardial infarction.

Clinical chemistry - 1 Jul 2008

Domingues-Montanari Sophie, Subirana Isaac, Tomás Marta, Marrugat Jaume, Sentí Mariano

Abstract excerpt

BACKGROUND: Environmental and genetic factors contribute to the development of complex diseases such as myocardial infarction (MI), the leading cause of death in men and women. Women develop MI approximately 10 years later than men, a difference that could be explained by the genes coding for the estrogen receptors. Single nucleotide polymorphisms (SNPs) in the ESR2 gene may affect susceptibility for MI in a...

Topics

Case-Control Studies
Cross-Sectional Studies
Estrogen Receptor beta
Female
Genetic Predisposition to Disease
Humans
Male
Middle Aged
Myocardial Infarction
Polymorphism, Single Nucleotide
Risk Assessment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sex Factors

Source

Identifiers

PMID: 18487282
DOI: 10.1373/clinchem.2007.102400

Genes

ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Association between ESR2 genetic variants and risk of myocardial infarction.PMID 18487282Read ↗

Polymorphisms and Haplotypes of the Estrogen Receptor-β Gene (ESR2) and Cardiovascular Disease in Men and WomenSemantic proximity Read ↗

Estrogen receptor alpha gene polymorphisms and risk of myocardial infarction.Semantic proximity Read ↗

Association between estrogen receptor alpha gene variation and cardiovascular disease.Semantic proximity Read ↗

The rs9982601 polymorphism of the region between the SLC5A3/MRPS6 and KCNE2 genes associated with a prevalence of myocardial infarction and subsequent long-term mortality.Semantic proximity Read ↗

Estrogen receptor alpha gene variation is associated with risk of myocardial infarction in more than seven thousand men from five cohorts.Semantic proximity Read ↗

ESR2 gene G1730A variant is associated with triglycerides level and myocardial infarction in young men but not in women.Semantic proximity Read ↗

No replication of association between estrogen receptor alpha gene polymorphisms and susceptibility to myocardial infarction in a large sample of patients of European descent.Semantic proximity Read ↗

Qualitative assessment of previous evidence and an updated meta-analysis confirms lack of association between the ESR1 rs2234693 (PvuII) variant and coronary heart disease in men and women.Semantic proximity Read ↗

Genetic polymorphisms in the ESR1 gene and cerebral infarction risk: a meta-analysis.Semantic proximity Read ↗

Takotsubo syndrome and estrogen receptor genes: partners in crime?Semantic proximity Read ↗

Genetic variance in CYP2C8 and increased risk of myocardial infarction.Semantic proximity Read ↗

Genetic variants associated with myocardial infarction risk factors in over 8000 individuals from five ethnic groups: The INTERHEART Genetics Study.Semantic proximity Read ↗

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