Article
Estrogen receptor 1 gene polymorphisms and coronary artery disease in the Brazilian population.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Apr 2006
Almeida S, Hutz M H
Abstract excerpt
We examined the association of three established single nucleotide polymorphisms, IVS1-397T>C, IVS1-351A>G, and +261G>C, in the ESR1 gene with the prevalence and severity of coronary atherosclerosis in a southern Brazilian population of European ancestry. Three hundred and forty-one subjects (127 women and 214 men) with coronary artery disease (CAD) were classified as having significant disease (CAD+ patient...
Topics
- Brazil
- Case-Control Studies
- Coronary Artery Disease
- Estrogen Receptor alpha
- Female
- Genetic Markers
- Genetic Predisposition to Disease
- Humans
- Logistic Models
- Male
- Middle Aged
