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Article

Estrogen receptor-1 genotype is related to coronary intima thickness in young to middle-aged women.

Scandinavian journal of clinical and laboratory investigation - 1 Jan 2007

Henttonen A T, Kortelainen M-L, Kunnas T A, Nikkari S T

Abstract excerpt

OBJECTIVE: The incidence of coronary disease in premenopausal women is about one-half that in men of similar age. The estrogen receptor-1 (ESR1, c.454-397T>C) CC variant genotype is associated with the severity of coronary artery disease (CAD) and an increased risk of myocardial infarction in men. The purpose of the present study was to investigate whether this ESR1 CC variant also disposes to atherosclerosis in...

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Source

Identifiers

PMID: 17558892
DOI: 10.1080/00365510601085951

Genes

ESR1
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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