Article
Association of polymorphisms in the sex hormone genes with the presence and severity of coronary artery disease.
Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir - 1 Jan 2022
Çoban Neslihan, Özuynuk Aybike Sena, Erkan Aycan Fahri, Kaya Ayşem, Ekici Berkay, Güçlü-Geyik Filiz, Ademoğlu Evin, Can Günay, Erginel-Ünaltuna Nihan
Abstract excerpt
OBJECTIVE: Coronary artery disease (CAD) is an important public health problem worldwide. Therefore, it is important to identify the molecular mechanisms and the candidate gene polymorphisms involved in the development of CAD. In this study, we focused on 2 polymorphisms of the atherosclerosis-related genes, ESR1 and CYP19A1. METHODS: Unselected 339 individuals who underwent coronary angiography were divided into...
Topics
- Alleles
- Coronary Angiography
- Coronary Artery Disease
- Female
- Genetic Predisposition to Disease
- Gonadal Steroid Hormones
- Humans
- Male
- Polymorphism, Genetic
- Risk Factors
