Article
Cryptococcosis in beige mice: the effect of congenital defects in innate immunity on susceptibility.
Canadian journal of microbiology - 1 Feb 1991
Salkowski C A, Balish E
Abstract excerpt
The influence of the beige (bg/bg) mutation on susceptibility to cryptococcosis was assessed by mortality, quantitative culturing, and histopathology of infected organs from bg/bg and bg/+ mice. Immunodeficient bg/bg mice were more susceptible to systemic cryptococcosis than immunocompetent bg/+ mice. Differences in susceptibility of bg/bg and bg/+ mice corresponded with temporal differences in histopathology. In...
Topics
- Animals
- Brain
- Cryptococcosis
- Genetic Predisposition to Disease
- Genotype
- Germ-Free Life
- Hair Color
- Immunity, Innate
- Kidney
- Liver
- Lung
- Mice