Article
Candidiasis in interferon-gamma knockout (IFN-gamma-/-) mice.
The Journal of infectious diseases - 1 Aug 1998
Balish E, Wagner R D, Vázquez-Torres A, Pierson C, Warner T
Abstract excerpt
Germ-free C57BL/6 x 129 interferon-gamma knockout (IFN-gamma(-/-)) mice and their immunocompetent (+/-, +/+) counterparts were colonized with a pure culture of Candida albicans to assess their natural susceptibility to mucosal and systemic candidiasis of endogenous origin. Colonization with a pure culture of C. albicans was not lethal for adult or neonatal IFN-gamma(-/-) gnotobiotic mice over the 15-week study....
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