Article
Candida glabrata intra-abdominal candidiasis is characterized by persistence within the peritoneal cavity and abscesses.
Infection and immunity - 1 Jul 2014
Cheng Shaoji, Clancy Cornelius J, Hartman Douglas J, Hao Binghua, Nguyen M Hong
Abstract excerpt
The pathogenesis of Candida glabrata infections is poorly understood. We studied the pathogenesis of intra-abdominal candidiasis (IAC) in mice that were infected intraperitoneally with C. glabrata and sterile feces. C. glabrata BG2 (5 × 10(8) CFU) caused a 100% mortality rate. Sublethal inocula of BG2 (1 × 10(8) or 1 × 10(7) CFU) caused peritonitis that progressed to abscesses. Three clinical C. glabrata strains...
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