Article
Effects of the beige mutation on respiratory tract infection with Pseudomonas aeruginosa in mice.
Experimental lung research - 1 Jan 2000
Tanaka E, Yuba Y, Sato A, Kuze F
Abstract excerpt
The role of neutrophil proteinases in the pathogenesis of respiratory tract infections with Pseudomonas aeruginosa was evaluated by studying the course of murine respiratory tract infection with a clinical isolate of P. aeruginosa mucoid strain developed by the agarose beads method in C57BL/6J(bg/bg) mice (beige mice). Neutrophils of beige mice are known to have defects in elastase and cathepsin G, but to have...
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