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Article

Dysregulated Inflammatory Response toCandida albicansin a C5-Deficient Mouse Strain

22 Sept 2004

Abstract excerpt

Experimental infection of inbred mouse strains with Candida albicans provides a good model system to identify host genetic determinants that regulate onset of, response to, and ultimate outcome of disseminated candidiasis. The A/J mouse strain is exquisitely sensitive to infection with C. albicans, while the C57BL/6J strain is relatively resistant, as measured by survival following intravenous injection of...

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PMID: 15385488
DOI: 10.1128/iai.72.10.5868-5876.2004

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