Article
Association of SLC6A12 variants with aspirin-intolerant asthma in a Korean population.
Annals of human genetics - 1 Jul 2010
Pasaje Charisse Flerida A, Kim Jeong-Hyun, Park Byung-Lae, Cheong Hyun Sub, Chun Ji-Yong, Park Tae-Joon, Lee Jin-Sol, Kim Yongha, Bae Joon Seol, Park Jong Sook, Yoon Sang-Hyuk, Uh Soo-Taek, Choi Jae-Sung, Kim Yong-Hoon, Kim Mi-Kyeong, Choi Inseon S, Cho Sang Heon, Choi Byoung Whui, Park Choon-Sik, Shin Hyoung Doo
Abstract excerpt
Aspirin-intolerant asthma (AIA) occurs from asthma exacerbation after exposure to aspirin. However, the underlying mechanisms of AIA occurrence are still unclear. The critical role of the solute carrier family 6 (neurotransmitter transporter, betaine/GABA) member 12 (SLC6A12) gene in GABAergic transmission, which is associated with mucus production in asthma, makes it a candidate gene for AIA association study....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.