Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide and follow-up studies identify CEP68 gene variants associated with risk of aspirin-intolerant asthma.

PloS one - 3 Nov 2010

Kim Jeong-Hyun, Park Byung-Lae, Cheong Hyun Sub, Bae Joon Seol, Park Jong Sook, Jang An Soo, Uh Soo-Taek, Choi Jae-Sung, Kim Yong-Hoon, Kim Mi-Kyeong, Choi Inseon S, Cho Sang Heon, Choi Byoung Whui, Park Choon-Sik, Shin Hyoung Doo

Abstract excerpt

Aspirin-intolerant asthma (AIA) is a rare condition that is characterized by the development of bronchoconstriction in asthmatic patients after ingestion of non-steroidal anti-inflammatory drugs including aspirin. However, the underlying mechanisms of AIA occurrence are still not fully understood. To identify the genetic variations associated with aspirin intolerance in asthmatics, the first stage of genome-wide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Inflammatory Agents, Non-Steroidal
Share to Aspirin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asthma

Share to Drug Hypersensitivity

Share to Follow-Up Studies

Share to Forced Expiratory Volume

Share to Linkage Disequilibrium

Share to Microtubule-Associated Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 21072201
DOI: 10.1371/journal.pone.0013818
PMCID: PMC2972220

Genes

CEP68
FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide and follow-up studies identify CEP68 gene variants associated with risk of aspirin-intolerant asthma.PMID 21072201Read ↗

Variants of CEP68 gene are associated with acute urticaria/angioedema induced by multiple non-steroidal anti-inflammatory drugs.Semantic proximity Read ↗

Exonic variants associated with development of aspirin exacerbated respiratory diseases.Semantic proximity Read ↗

Association of four-locus gene interaction with aspirin-intolerant asthma in Korean asthmatics.Semantic proximity Read ↗

Analysis of high-affinity IgE receptor (FcepsilonR1) polymorphisms in patients with aspirin-intolerant chronic urticaria.Semantic proximity Read ↗

Possible association of SLC22A2 polymorphisms with aspirin-intolerant asthma.Semantic proximity Read ↗

Positive association between aspirin-intolerant asthma and genetic polymorphisms of FSIP1: a case-case study.Semantic proximity Read ↗

Association of SLC6A12 variants with aspirin-intolerant asthma in a Korean population.Semantic proximity Read ↗

Lack of an association between a newly identified promoter polymorphism (-1702G > A) of the leukotriene C4 synthase gene and aspirin-intolerant asthma in a Korean population.Semantic proximity Read ↗

Polymorphisms in CEP68 gene associated with risk of immediate selective reactions to non-steroidal anti-inflammatory drugs.Semantic proximity Read ↗

Effect of single nucleotide polymorphisms within the interleukin-4 promoter on aspirin intolerance in asthmatics and interleukin-4 promoter activity.Semantic proximity Read ↗

Association of angiotensin I-converting enzyme gene polymorphisms with aspirin intolerance in asthmatics.Semantic proximity Read ↗

Association between polymorphisms in prostanoid receptor genes and aspirin-intolerant asthma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.