Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A new association between polymorphisms of the SLC6A7 gene in the chromosome 5q31-32 region and asthma.

Journal of human genetics - 1 Jun 2010

Kim Jeong-Hyun, Cheong Hyun Sub, Park Byung-Lae, Bae Joon Seol, Jung Seok, Yoon Sang-Hyuk, Park Jong Sook, Jang An Soo, Park Sung Woo, Uh Soo-Taek, Kim Yong-Hoon, Hwang Hyeon-Kyu, Park Choon-Sik, Shin Hyoung Doo

Abstract excerpt

The human chromosomal 5q31-33 region has been implicated as a susceptibility locus for several immune-mediated diseases including asthma in several populations. Recently, the extraneuronal GABAergic system has been implicated as a new link to airway obstruction in asthma. In addition, the SLC6A7 gene, which is positioned at 5q31-32 and encodes the transporter for an excitatory neurotransmitter of L-proline, has...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Transport Systems, Neutral
Share to Asthma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 5

Share to Genome-Wide Association Study

Share to Introns

Share to Linkage Disequilibrium

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 20431603
DOI: 10.1038/jhg.2010.34

Genes

MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A new association between polymorphisms of the SLC6A7 gene in the chromosome 5q31-32 region and asthma.PMID 20431603Read ↗

Association of 5-hydroxytryptamine (serotonin) receptor 4 (5-HTR4) gene polymorphisms with asthma.Semantic proximity Read ↗

Association between brain-derived neurothropic factor variants and asthma in Chinese Han children.Semantic proximity Read ↗

Gene-based single nucleotide polymorphisms and linkage disequilibrium patterns of 29 asthma candidate genes in the chromosome 5q31-33 region in Koreans.Semantic proximity Read ↗

Sequence variants on 17q21 are associated with the susceptibility of asthma in the population of Lahore, Pakistan.Semantic proximity Read ↗

Association between ADAM33 gene polymorphisms and asthma in the Zhuang population of China.Semantic proximity Read ↗

Asthma and atopy are associated with chromosome 17q21 markers in Chinese children.Semantic proximity Read ↗

Association between a functional single nucleotide polymorphism in the brain-derived neurotrophic factor gene and risk of child asthma.Semantic proximity Read ↗

Association between β2-adrenoceptor gene polymorphisms and asthma risk: an updated meta-analysis.Semantic proximity Read ↗

Single nucleotide polymorphisms in the promoter region of mir-133a-1 and in pre-mir-152 rs1707 may contribute to the risk of asthma in a Chinese Han population.Semantic proximity Read ↗

Association between Val66Met polymorphisms in brain-derived neurotrophic factor gene and asthma risk: a meta-analysis.Semantic proximity Read ↗

Single-Nucleotide Polymorphisms of IL-17 Gene Are Associated with Asthma Susceptibility in an Asian Population.Semantic proximity Read ↗

Association of SLC6A12 variants with aspirin-intolerant asthma in a Korean population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.