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Article

Association analysis of N-acetyl transferase-2 polymorphisms with aspirin intolerance among asthmatics.

Pharmacogenomics - 1 Jul 2010

Kim Jin-Moo, Park Byung-Lae, Park Se-Min, Lee Shin-Hwa, Kim Myung-Ok, Jung Seok, Lee Eun Hee, Uh Soo-Taek, Park Jong Sook, Choi Jae-Sung, Kim Yong-Hoon, Kim Mi-Kyeong, Choi Inseon S, Cho Sang Heon, Choi Byoung Whui, Park Hae-Sim, Chang Hun Soo, Shin Hyoung Doo, Park Choon-Sik

Abstract excerpt

AIMS: Cysteinyl leukotrienes are inactivated by acetyl coenzyme A-dependent N-acetyltransferase (NAT). Thus, functional alterations of the NAT gene may contribute to the risk of aspirin-intolerant asthma. MATERIALS & METHODS: Asthmatics (n = 438) were categorized into aspirin-intolerant asthma (15% or greater decrease in the forced expiratory volume in 1 s or cutaneous reactions, n = 170) or aspirin-tolerant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20602614
DOI: 10.2217/pgs.10.65

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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