Article
Positive association between aspirin-intolerant asthma and genetic polymorphisms of FSIP1: a case-case study.
BMC pulmonary medicine - 1 Jun 2010
Kim Jason Yongha, Kim Jeong Hyun, Park Tae Joon, Bae Joon Seol, Lee Jin Sol, Pasaje Charisse Flerida, Park Byung Lae, Cheong Hyun Sub, Park Jong-Sook, Park Sung-Woo, Uh Soo-Taek, Kim Mi-Kyeong, Choi Inseon S, Cho Sang Heon, Choi Byoung Whui, Park Choon-Sik, Shin Hyoung Doo
Abstract excerpt
BACKGROUND: Aspirin-intolerant asthma (AIA), which is caused by non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin, causes lung inflammation and reversal bronchi reduction, leading to difficulty in breathing. Aspirin is known to affect various parts inside human body, ranging from lung to spermatogenesis. FSIP1, also known as HDS10, is a recently discovered gene that encodes fibrous sheath interacting...
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