Article
Association of CACNG6 polymorphisms with aspirin-intolerance asthmatics in a Korean population.
BMC medical genetics - 23 Sept 2010
Lee Jin Sol, Kim Jeong-Hyun, Bae Joon Seol, Kim Jason Yongha, Park Tae Joon, Pasaje Charisse Flerida, Park Byung-Lae, Cheong Hyun Sub, Uh Soo-Taek, Park Jong-Sook, Jang An-Soo, Kim Mi-Kyeong, Choi Inseon S, Park Choon-Sik, Shin Hyoung Doo
Abstract excerpt
BACKGROUND: Aspirin-intolerant asthma (AIA) occurs in the lower and upper airways through excessive production of leukotrienes upon administration of non-steroidal anti-inflammatory drugs (NSAIDs). One of the three symptoms of AIA is nasal polyposis, a chronic inflammatory disease that is related to the function of calcium ion in recruitment of immune cells during airway inflammation. It has been implicated that...
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