Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aurora kinase A as a rational target for therapy in glioblastoma

1 Jul 2010

Abstract excerpt

OBJECT: Despite advances in the knowledge of tumor biology, the outcome of glioblastoma tumors remains poor. The design of many molecularly targeted therapies in glioblastoma has focused on inhibiting molecular abnormalities present in tumor cells compared with normal tissue rather than patient outcome-associated factors. As an alternative approach, the present study identified genes associated with shorter...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Microtubule and mitosis dynamics
Share to Neuroblastoma Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20593995
DOI: 10.3171/2010.3.peds10120

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aurora kinase A as a rational target for therapy in glioblastomaPMID 20593995Read ↗

Aurora A is differentially expressed in gliomas, is associated with patient survival in glioblastoma and is a potential chemotherapeutic target in gliomasSemantic proximity Read ↗

Aurora Kinase Inhibitors - Rising Stars in Cancer Therapeutics?Semantic proximity Read ↗

Aurora kinases signaling in cancer: from molecular perception to targeted therapiesSemantic proximity Read ↗

Aurora-A Kinase as a Promising Therapeutic Target in CancerSemantic proximity Read ↗

Aurora B expression correlates with aggressive behaviour in glioblastoma multiformeSemantic proximity Read ↗

Targeting AURKA in Cancer: molecular mechanisms and opportunities for Cancer therapySemantic proximity Read ↗

Aurora Kinases as Anticancer Drug TargetsSemantic proximity Read ↗

Aurora Kinases: New Targets for Cancer TherapySemantic proximity Read ↗

Biology of Aurora A kinase: Implications in cancer manifestation and therapySemantic proximity Read ↗

Aurora kinase inhibitors as anti-cancer therapySemantic proximity Read ↗

Aurora Kinase B Inhibition: A Potential Therapeutic Strategy for CancerSemantic proximity Read ↗

Functional Significance of Aurora Kinases–p53 Protein Family Interactions in CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.