Article
Interactions among related genes of renin-angiotensin system associated with type 2 diabetes.
Diabetes care - 1 Oct 2010
Yang Jin-Kui, Zhou Jian-Bo, Xin Zhong, Zhao Lei, Yu Mei, Feng Jian-Ping, Yang Hui, Ma Ya-Hong
Abstract excerpt
OBJECTIVE: To explore the association between epistasis among related genes of the renin-angiotensin system (RAS) and type 2 diabetes. RESEARCH DESIGN AND METHODS: Gene polymorphisms were genotyped in 394 type 2 diabetic patients and 418 healthy control subjects in this case-control study. We used the multifactor dimensionality reduction method to identify gene-gene interactions. RESULTS: No single locus was...
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