Article
Gene-gene interactions among genetic variants from obesity candidate genes for nonobese and obese populations in type 2 diabetes.
Genetic testing and molecular biomarkers - 1 Aug 2009
Lin Eugene, Pei Dee, Huang Yi-Jen, Hsieh Chang-Hsun, Wu Lawrence Shih-Hsin
Abstract excerpt
Recent studies indicate that obesity may play a key role in modulating genetic predispositions to type 2 diabetes (T2D). This study examines the main effects of both single-locus and multilocus interactions among genetic variants in Taiwanese obese and nonobese individuals to test the hypothesis that obesity-related genes may contribute to the etiology of T2D independently and/or through such complex...
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