Article
Association between polymorphisms of the renin-angiotensin system and coronary artery disease in Chinese patients with type 2 diabetes.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Jun 2012
Lei He-Ping, Chen Hong-Mei, Zhong Shi-Long, Yao Qing-Zhou, Tan Hong-Hong, Yang Min, Lin Qiu-Xiong, Shan Zhi-Xin, Zheng Zhi-Wei, Zhu Jie-Ning, Zhou Zhi-Ling, Lin Shu-Guang, Yu Xi-Yong
Abstract excerpt
BACKGROUND: The renin-angiotensin system (RAS) is regarded as one of the most important regulatory systems for cardiovascular homeostasis. In this study, we investigated associations of the five genetic polymorphisms in the RAS and presence of coronary artery disease (CAD) in type 2 diabetes. METHODS: Genotyping was performed by polymerase chain reaction-restriction fragment length polymorphism analysis. We used...
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