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Article

Interactions of renin-angiotensin system gene polymorphisms and antihypertensive effect of benazepril in Chinese population.

Pharmacogenomics - 1 May 2011

Chen Qing, Yu Can-Qing, Tang Xun, Chen Da-Fang, Tian Jun, Cao Yang, Fan Wen-Yi, Cao Wei-Hua, Zhan Si-Yan, Lv Jun, Guo Xiao-Xia, Hu Yong-Hua, Lee Li-Ming

Abstract excerpt

AIM: Angiotensin-converting enzyme inhibitors are widely used antihypertensive drugs with individual response variation. We studied whether interactions of AGT, AGTR1 and ACE2 gene polymorphisms affect this response. MATERIALS & METHODS: Our study is based on a 3-year field trial with 1831 hypertensive patients prescribed benazepril. Generalized multifactor dimensionality reduction was used to explore interaction...

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Source

Identifiers

PMID: 21449848
DOI: 10.2217/pgs.11.2

Genes

AGT
ACE2
AGTR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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