Article
Renin-Angiotensin System Gene Variants and Type 2 Diabetes Mellitus: Influence of Angiotensinogen.
Journal of diabetes research - 1 Jan 2016
Joyce-Tan Siew Mei, Zain Shamsul Mohd, Abdul Sattar Munavvar Zubaid, Abdullah Nor Azizan
Abstract excerpt
Genome-wide association studies (GWAS) have been successfully used to call for variants associated with diseases including type 2 diabetes mellitus (T2DM). However, some variants are not included in the GWAS to avoid penalty in multiple hypothetic testing. Thus, candidate gene approach is still useful even at GWAS era. This study attempted to assess whether genetic variations in the renin-angiotensin system (RAS)...
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