Article
Analysis of epistasis for diabetic nephropathy among type 2 diabetic patients.
Human molecular genetics - 15 Sept 2006
Hsieh Chang-Hsun, Liang Kung-Hao, Hung Yi-Jen, Huang Li-Chin, Pei Dee, Liao Ya-Tang, Kuo Shi-Wen, Bey Monica Shian-Jy, Chen Jui-Lin, Chen Ellson Y
Abstract excerpt
Diabetic nephropathy (DN) is one of the most serious complications of diabetes, accounting for the majority of patients with end-stage renal disease. The molecular pathogenesis of DN involves multiple pathways in a complex, partially resolved manner. The paper presents an exploratory epistatic study for DN. Association analysis were performed on 231 SNP loci in a cohort of 264 type 2 diabetes patients, followed...
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