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Article

Gene-gene interactions lead to higher risk for development of type 2 diabetes in a Chinese Han population: a prospective nested case-control study.

Lipids in health and disease - 28 Jul 2018

Zhou Wen, Li Yuqian, Zhang Lulu, Shi Yuanyuan, Wang Chongjian, Zhang Dongdong, Liu Xuejiao, Mao Zhenxing, Li Linlin

Abstract excerpt

BACKGROUND: The purpose of this study was to evaluate the effect of single-nucleotide polymorphisms (SNPs) of the GCKR and G6PC2 genes on risk for type 2 diabetes and the SNP-SNP and haplotype-based interactions between these genes. METHODS: Subjects of this nested case-control study were selected from a prospective cohort residing in the rural area of Luoyang city in China. Cases (n = 538) were individually...

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Identifiers

PMID: 30055620
DOI: 10.1186/s12944-018-0813-6
PMCID: PMC6064617

Genes

GCKR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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