Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transforming growth factor beta 2 and heme oxygenase 1 genes are risk factors for the cerebral malaria syndrome in Angolan children.

PloS one - 16 Jun 2010

Sambo Maria Rosário, Trovoada Maria Jesus, Benchimol Carla, Quinhentos Vatúsia, Gonçalves Lígia, Velosa Rute, Marques Maria Isabel, Sepúlveda Nuno, Clark Taane G, Mustafa Stefan, Wagner Oswald, Coutinho António, Penha-Gonçalves Carlos

Abstract excerpt

BACKGROUND: Cerebral malaria (CM) represents a severe outcome of the Plasmodium falciparum infection. Recent genetic studies have correlated human genes with severe malaria susceptibility, but there is little data on genetic variants that increase the risk of developing specific malaria clinical complications. Nevertheless, susceptibility to experimental CM in the mouse has been linked to host genes including...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angola
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Markers

Share to Heme Oxygenase (Decyclizing)

Share to Linkage Disequilibrium

Share to Malaria, Cerebral

Share to Malaria, Falciparum

Share to Transforming Growth Factor beta2

Source

Open in PubMed Open full text

Identifiers

PMID: 20585394
DOI: 10.1371/journal.pone.0011141
PMCID: PMC2886838

Genes

HMOX1
TGFB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transforming growth factor beta 2 and heme oxygenase 1 genes are risk factors for the cerebral malaria syndrome in Angolan children.PMID 20585394Read ↗

Host susceptibility to malaria in human and mice: compatible approaches to identify potential resistant genes.Semantic proximity Read ↗

Genetics of Malaria Inflammatory Responses: A Pathogenesis PerspectiveSemantic proximity Read ↗

New insights into malaria susceptibility from the genomes of 17,000 individuals from Africa, Asia, and OceaniaSemantic proximity Read ↗

Overview of human genetic susceptibility to malaria: From parasitemia control to severe disease.Semantic proximity Read ↗

How malaria has affected the human genome and what human genetics can teach us about malaria.Semantic proximity Read ↗

Association of candidate gene polymorphisms and TGF-beta/IL-10 levels with malaria in three regions of Cameroon: a case-control study.Semantic proximity Read ↗

Genetic susceptibility to malaria and other infectious diseases: from the MHC to the whole genome.Semantic proximity Read ↗

Cyclooxygenase-2 haplotypes influence the longitudinal risk of malaria and severe malarial anemia in Kenyan children from a holoendemic transmission region.Semantic proximity Read ↗

Susceptibility to malaria as a complex trait: big pressure from a tiny creature.Semantic proximity Read ↗

Familial aggregation of cerebral malaria and severe malarial anemia.Semantic proximity Read ↗

Age-related susceptibility to severe malaria associated with galectin-2 in highland Papuans.Semantic proximity Read ↗

HMOX1 STR polymorphism and malaria: an analysis of a large clinical dataset.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.