Article
Susceptibility to malaria as a complex trait: big pressure from a tiny creature.
Human molecular genetics - 1 Oct 2002
Fortin A, Stevenson M M, Gros P
Abstract excerpt
Malaria, which is a major infectious disease worldwide, is caused by the Plasmodium parasite, one of the longest-known parasites infecting humans. The malaria situation is complicated by the emergence of drug resistance and the lack of an effective vaccine. Genetic factors play a key role in disease susceptibility, progression and outcome. Interestingly, an increasing large number of polymorphisms associated with...
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