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Article

Weak CD4+ T-cell responses to citrullinated vimentin in rheumatoid arthritis patients carrying HLA-DR9 alleles.

Rheumatology international - 1 Jun 2012

Catalán Diego, Aravena Octavio, Zúñiga Roberto, Silva Natalia, Escobar Alejandro, Sabugo Francisca, Wurmann Pamela, Soto Lilian, González Rodrigo, Alfaro Jorge, Larrondo Milton, Cuchacovich Miguel, Aguillón Juan Carlos

Abstract excerpt

Citrullinated vimentin (cVIM) is one of the antigens specifically targeted by anti-citrullinated protein antibodies (ACPA) in rheumatoid arthritis (RA) patients. The association between ACPA and certain HLA-DRB1 alleles, those coding for the shared epitope (SE), suggests that this response could...

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Share to Autoantibodies
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Citrulline

Share to HLA-DR Serological Subtypes

Share to Immunodominant Epitopes

Share to Lymphocyte Activation

Share to Vimentin

Source

Identifiers

PMID: 21769486
DOI: 10.1007/s00296-011-2039-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21769486-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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