Article
Relationship of the HLA-DRB1 alleles and seropositivity, anti-MCV, functional status and radiological damage in Turkish patients with rheumatoid arthritis.
Journal of back and musculoskeletal rehabilitation - 1 Jan 2013
Sariyildiz Mustafa Akif, Batmaz Ibrahim, Guli Çetinçakmak Mehmet, Yıldız Ismail, Nas Kemal, Çevik Remzi
Abstract excerpt
OBJECTIVES: The HLA-DRB1 gene plays an important role in the genetic predisposition to rheumatoid arthritis. The anti-citrullinated protein antibody (ACPA) is known to be associated with the susceptibility to rheumatoid arthritis (RA), as well as the severity of the disease. The aim of this study is to determine the HLA genes that are associated with the severity of the RA measured by seropositivity, functional...
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