Article
SNP-SNP interactions between WNT4 and WNT5A were associated with obesity related traits in Han Chinese Population.
Scientific reports - 8 Mar 2017
Dong Shan-Shan, Hu Wei-Xin, Yang Tie-Lin, Chen Xiao-Feng, Yan Han, Chen Xiang-Ding, Tan Li-Jun, Tian Qing, Deng Hong-Wen, Guo Yan
Abstract excerpt
Considering the biological roles of WNT4 and WNT5A involved in adipogenesis, we aimed to investigate whether SNPs in WNT4 and WNT5A contribute to obesity related traits in Han Chinese population. Targeted genomic sequence for WNT4 and WNT5A was determined in 100 Han Chinese subjects and tag SNPs were selected. Both single SNP and SNP × SNP interaction association analyses with body mass index (BMI) were evaluated...
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