Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A combination of proatherogenic single-nucleotide polymorphisms is associated with increased risk of coronary artery disease and myocardial infarction in Asian Indians.

DNA and cell biology - 1 Sept 2009

Poduri Aruna, Khullar Madhu, Bahl Ajay, Sharma Yash Paul, Talwar Kewal K

Abstract excerpt

Common single-nucleotide polymorphisms (SNPs) in genes of lipid metabolism modestly influence plasma low-density lipoprotein cholesterol (LDL-C) and risk of coronary artery disease (CAD). We evaluated a panel of LDL-C-modulating SNPs for potential association with risk of CAD in Asian Indians. Fifteen SNPs of CETP, ABCB1, APOAI, CYP7A1, and HMGCR genes were genotyped in 265 CAD patients and 150 controls of North...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein A-I
Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Share to Cholesterol 7-alpha-Hydroxylase

Share to Cholesterol Ester Transfer Proteins

Share to Cholesterol, HDL

Share to Cholesterol, LDL

Share to Hydroxymethylglutaryl CoA Reductases

Source

Identifiers

PMID: 19558216
DOI: 10.1089/dna.2009.0887

Genes

CAD
ABCB1
CETP
HMGCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A combination of proatherogenic single-nucleotide polymorphisms is associated with increased risk of coronary artery disease and myocardial infarction in Asian Indians.PMID 19558216Read ↗

Common variants of HMGCR, CETP, APOAI, ABCB1, CYP3A4, and CYP7A1 genes as predictors of lipid-lowering response to atorvastatin therapy.Semantic proximity Read ↗

Genetic variants influencing circulating lipid levels and risk of coronary artery disease.Semantic proximity Read ↗

Common genetic variation in six lipid-related and statin-related genes, statin use and risk of incident nonfatal myocardial infarction and stroke.Semantic proximity Read ↗

Gene-drug interactions identify genomic loci that enhance statin effectiveness in lowering LDL cholesterolSemantic proximity Read ↗

Genetic Polymorphisms and Genetic Risk Scores Contribute to the Risk of Coronary Artery Disease (CAD) in a North Indian Population.Semantic proximity Read ↗

Gene-statin interaction study identifies 9 loci that moderate statin effectiveness in blood lipidsSemantic proximity Read ↗

Biological, clinical and population relevance of 95 loci for blood lipids.Semantic proximity Read ↗

Genetic variants associated with myocardial infarction risk factors in over 8000 individuals from five ethnic groups: The INTERHEART Genetics Study.Semantic proximity Read ↗

Genome-wide meta-analysis of phytosterols reveals five novel loci and a detrimental effect on coronary atherosclerosis.Semantic proximity Read ↗

A genome wide association study identifies common variants associated with lipid levels in the Chinese population.Semantic proximity Read ↗

A meta-analysis of three identified single nucleotide polymorphisms at 1p13.3 and 1q41 and their associations with lipid levels and coronary artery disease.Semantic proximity Read ↗

Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.