Article
Heme oxygenase-1 gene promoter polymorphism is associated with risk of gastric adenocarcinoma and lymphovascular tumor invasion.
Annals of surgical oncology - 1 Aug 2007
Lo Su-Shun, Lin Shu-Chun, Wu Chew-Wun, Chen Jen-Hao, Yeh Wen-I, Chung Ming-Yi, Lui Win-Yiu
Abstract excerpt
PURPOSE: Heme oxygenase-1 (HO-1) gene, which encodes an oxidative response protein, plays a role in cytoprotection. A (GT)n dinucleotide repeat in HO-1 promoter is polymorphic and modulates the transcriptional activity of the gene. A HO-1 gene promoter polymorphism was reported to be associated w...
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