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Article

The ALDH2 and DRD2/ANKK1 genes interacted in bipolar II but not bipolar I disorder.

Pharmacogenetics and genomics - 1 Aug 2010

Lee Sheng-Yu, Chen Shiou-Lan, Chang Yun-Hsuan, Chen Shih-Heng, Chu Chun-Hsieh, Huang San-Yuan, Tzeng Nian-Sheng, Wang Chen-Lin, Lee I Hui, Yeh Tzung Lieh, Yang Yen Kuang, Lu Ru-Band

Abstract excerpt

AIM: Clarifying the association between bipolar I and bipolar II, the two most common subtypes of bipolar disorder, at the genetic level is essential for improving our understanding of these disorders. The dopaminergic system has been implicated in the pathogenesis of bipolar disorder. It may be important to investigate genes involved in metabolizing dopamine and encoding dopamine receptors, such as the aldehyde...

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Source

Identifiers

PMID: 20577142
DOI: 10.1097/FPC.0b013e32833caa2b

Genes

ALDH2
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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