Article
The interaction between BDNF and DRD2 in bipolar II disorder but not in bipolar I disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2012
Huang Chih-Chun, Chang Yun-Hsuan, Lee Sheng-Yu, Chen Shiou-Lan, Chen Shih-Heng, Chu Chun-Hsien, Huang San-Yuan, Tzeng Nian-Sheng, Lee I Hui, Yeh Tzung Lieh, Yang Yen Kuang, Lu Ru-Band
Abstract excerpt
Bipolar I (BP-I) and bipolar II (BP-II) disorders are the two most common subtypes of bipolar disorder. However, most studies have not differentiated bipolar disorder into BP-I and BP-II groups, for which the underlying etiology differentiating these two subtypes remains unclear. The genetic association between both subtypes is essential for improving our understanding. The dopamine D2 receptor/ankyrin repeat and...
Topics
- Adult
- Bipolar Disorder
- Brain-Derived Neurotrophic Factor
- Case-Control Studies
- Epistasis, Genetic
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Humans
- Logistic Models
- Male
- Polymorphism, Single Nucleotide