Article
Linkage and association between serotonin 2A receptor gene polymorphisms and bipolar I disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 15 Aug 2003
Ranade Swati S, Mansour Hader, Wood Joel, Chowdari Kodavali V, Brar Laurie K, Kupfer David J, Nimgaonkar Vishwajit L
Abstract excerpt
Several inconsistent associations between bipolar I disorder (BD1) and polymorphisms of the genes encoding the serotonin 2A receptor (HTR2A) have been published. We conducted the Transmission Disequilibrium Test (TDT) and case-control comparisons involving nine single nucleotide polymorphisms at the serotonin 2A receptor gene (four SNPs of HTR2A exons and five flanking SNPs). Comparison of BD1 cases (n = 93) with...
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